Pancreatic cancer is difficult to detect and diagnose for the following reasons: There are no noticeable signs or symptoms in the early stages of pancreatic cancer. The signs of pancreatic cancer, when present, are like the signs of many other illnesses, such as pancreatitis or an ulcer. The pancreas is obscured by other organs in the abdomen and is difficult to visualize clearly on imaging tests.
N Engl J Med. Randomized phase III study of weekly nab-paclitaxel plus gemcitabine versus gemcitabine alone in patients with metastatic adenocarcinoma of the pancreas MPACT. J Clin Oncol September 06, ; Accessed: Capecitabine plus erlotinib in gemcitabine-refractory advanced pancreatic cancer.
Final results of the randomized, prospective multicenter phase III trial of adjuvant chemotherapy with gemcitabine versus observation in patients with resected pancratic cancer.
June 4, ; Accessed: June 04, ; Accessed: Maisonneuve P, Lowenfels AB. Epidemiology of pancreatic cancer: Nat Rev Gastroenterol Hepatol. Diabetes, antidiabetic medications, and pancreatic cancer risk: Body mass index and risk, age of onset, and survival in patients with pancreatic cancer.
A pooled analysis of 14 cohort studies of anthropometric factors and pancreatic cancer risk. Body mass index and body size in early adulthood and risk of pancreatic cancer in a central European multicenter case-control study. Dietary intake of lycopene is associated with reduced pancreatic cancer risk.
Etiology of pancreatic cancer, with a hypothesis concerning the role of N-nitroso compounds and excess gastric acidity. J Natl Cancer Inst. Meat and fat intake as risk factors for pancreatic cancer: Risk of pancreatic cancer in relation to alcohol drinking, coffee consumption and medical history: Pancreatitis and the risk of pancreatic cancer.
International Pancreatitis Study Group. Cowgill SM, Muscarella P. The genetics of pancreatic cancer. Alcohol Clin Exp Res. Genetic predisposition to pancreatic cancer: Molecular biology of exocrine pancreatic cancer. Molecular genetics of exocrine pancreatic neoplasms. Surg Clin North Am.
Molecular characterization of pancreatic neoplasms. Germline BRCA2 gene mutations in patients with apparently sporadic pancreatic carcinomas. Molecular analysis to detect pancreatic ductal adenocarcinoma in high-risk groups. Inactivation of Smad4 accelerates Kras G12D -mediated pancreatic neoplasia.
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Distant metastasis occurs late during the genetic evolution of pancreatic cancer. The patterns and dynamics of genomic instability in metastatic pancreatic cancer.
Management of pancreatic endocrine tumors in multiple endocrine neoplasia type 1. Extra-intestinal manifestations of familial adenomatous polyposis. Cancer facts and figures for African Americans Cancer Epidemiol Biomarkers Prev.
Cancer of the pancreas. Cancer Epidemiology and Prevention. Oxford University Press; A novel prognostic scoring system using neutrophil-albumin ratio and Ca to predict overall survival in palliative pancreatic cancer. Suicide in patients with pancreatic cancer.Pancreatic Cancer Case Study- Background Chris is a year-old man from London.
Without any previous medical issues or problems, he was suddenly taken . When cancer researchers started to search for links between diet and cancer, one of the most noticeable findings was that people who avoided meat were much less likely to develop the disease. Patrick Swayze passed away Monday at the age of 57, but his month battle with pancreatic cancer highlighted the travails many sufferers face when they contract one of the deadliest forms of cancer.
Case Study: Pancreatic Adenocarcinoma. Pancreatic adenocarcinomas benefit from a multidisciplinary treatment approach. At Cleveland Clinic, a new pancreatic cancer clinic can help.
The results of case-control studies and anecdotal reports suggest that pancreatitis may be a risk factor for pancreatic cancer, but there have been no studies of sufficient size and power to.
Familial adenomatous polyposis a hereditary syndrome characterized by the formation of many polyps in the colon and rectum, some of which may develop into colorectal cancer.